Diana Wilkie

Diana Wilkie PhD, RN, FAAN


Department: Biobehavioral Nursing Science
Business Phone: (352) 273-6401
Business Email: diwilkie@ufl.edu

About Diana Wilkie

Diana Wilkie, Ph.D., R.N., FAAN, joined UF in 2015 as the Prairieview Trust – Earl and Margo Powers Endowed Professor in the Department of Biobehavioral Nursing Science. She also is the director of the Center for Palliative Care Research & Education, co-leader of Cancer Population Sciences in the UF Health Cancer Center, and co-director of the Florida-California Cancer Research, Education and Engagement (CaRE2) Health Equity Center.

Dr. Wilkie, a member of the National Academy of Medicine, has devoted her research program to management of cancer pain and to palliative care and end-of-life issues. Her research builds on pain problems she recognized through her clinical experience as a staff nurse, hospice nurse, and an oncology clinical nurse specialist. Her research has been continuously funded since 1986 from numerous organizations such as the National Institutes of Health, the American Cancer Society, Patient Centered Outcomes Research Institute, and the Robert Wood Johnson Foundation — totaling more than $64 million. This funding supports her biobehavioral and informatics research focused on pain, symptom science, and palliative care in populations spanning the life cycle with special focus on adults, older adults, and reducing health disparities.

Her clinical work with cancer patients led to the development of a tablet-based pain report system that allows a patient to describe his or her pain. The system automatically generates a report for the clinician with suggestions for appropriate interventions. The system also provides multimedia education on pain management for the patients and their family members. Wilkie recently completed a randomized clinical trial testing the effects of computerized pain tools on pain control for cancer patients receiving hospice care. She is testing a Turkish version of the pain report tool in Turkey with patients recovering from lung cancer surgery. She also recently completed a study focused on advanced care planning for African Americans with dementia, and three studies focused on understanding the mechanisms and genomics that contribute to the pain in sickle cell disease with a goal of improving outcomes for adults with sickle cell disease.

Currently she is leading a multi-site, randomized clinical trial of dignity therapy for elderly outpatients with cancer who are receiving palliative care. Study outcomes focus on key spiritual-related patient outcomes (dignity impact, existential tasks, and cancer prognosis awareness). The long-term goal of her research is to help clinicians effectively combine pharmacologic and nonpharmacologic therapies for management of pain as part of respectful care for individuals and families facing serious illness such as cancer and sickle cell disease.

Wilkie is a fellow of the American Academy of Nursing and served for five years as an American Cancer Society professor of oncology nursing. She has authored or co-authored more than 225 scholarly publications and 260 and serves as a reviewer on a number of journals, including the Journal of Palliative Medicine, Cancer Nursing and the Journal of Pain.

Wilkie has mentored more than 40 doctoral students, 13 postdoctoral scholars, and 9 junior faculty, including 2 supported by NRSA grants and 3 supported by diversity supplements with her as their primary mentor, and 21 individuals who were international scholars at the time she mentored them. She recently completed the University of Florida’s CTSI sponsored Mentorship Academy training and has a strong commitment to mentoring biobehavioral scientists who are focused on eliminating health disparities.

Honors & Awards

Elected member
2012-2019 · Institute of Medicine
Scholar Award
2012-2013 · University of Illinois
Information Technology Award for Clinical Nursing Applications for PAINReportIt®
2005 · Sigma Theta Tau International Honor Society of Nursing
Distinguished Alumna Award
2004 · Mesa College
Advancement of Science Award
2004 · Midwest Nursing Research Society End of Life and Palliative Care Research Section
Media Awards, Honorable Mention Award: TNEEL
2002 · American Academy of Nursing
2002 Pinnacle Awards: Computer-Based Professional Education Technology Award for Toolkit for Nursing Excellence at End-of-Life Transitions
2002 · Sigma Theta Tau International Honor Society of Nursing
10th Annual Distinguished Nurse Scholar Award
2002 · University of Detroit Mercy McAuley School of Nursing
R. Davilene Carter Presidential Prize for Best Paper
2000 · American Association for Cancer Education Annual Meeting
First Annual Research Award
1997 · National Hospice Foundation
Outstanding Public Service Award
1996 · University of Washington
Elected Fellow
1995 · American Academy of Nursing
Washington Division Professor of Oncology Nursing
1993-1998 · American Cancer Society
Dissertation Award
1991 · Region One (13 Western USA States), Sigma Theta Tau International
Carol A. Lindeman Award for a New Researcher
1991 · Western Society for Research in Nursing
Junior Investigator Travel Award
1990 · American Pain Society
Doctoral Class Commencement Speaker
1990 · University of California, School of Nursing
First Place, Doctoral Nursing
1990 · Graduate Students Association Research Award
Trainee Fellowship
1990 · International Pain Foundation, VIth World Congress on Pain
Nominee – Adria Excellence in Writing Award in Research
1989 · Oncology Nursing Society
First Place, Doctoral Nursing
1989 · Graduate Students Association Research Award
Trainee Fellowship
1988 · International Pain Foundation and the American Pain Society, Joint Meeting of the Canadian Pain Society and the American Pain Society
Trainee Fellowship
1987 · International Association for the Study of Pain, Vth World Congress on Pain
1986-1990 · National Cancer Institute Predoctoral Fellowship Award (1F32CA08256)
1985-1986 · Professional Nursing Title II Traineeship (2 A11 NU00289-10)
Nominee, Schering Excellence in Clinical Research Award
1985 · Oncology Nursing Society
1984 · Sigma Theta Tau, Nursing Honor Society
1982-1984 · American Cancer Society Master’s Scholarship Grant
1972-1976 · Gates Foundation Scholarship

Research Profile

Use of informatics to promote patient-centered care and big data science; pain assessment; biobehavioral therapies for cancer pain; behavioral correlates of cancer pain; palliative and end-of-life care; sickle cell disease pain mechanisms, assessment and management; reproductive choices for people with sickle cell disease or sickle cell trait; intervention research.


2018 American Journal of Hospice & Palliative Medicine
2017 AMIA … Annual Symposium proceedings / AMIA Symposium. AMIA Symposium


August 2019ACTIVE
Patterns of Marijuana Use for HIV Pain: A Mixed Methods Approach
September 2018ACTIVE
2/3 Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity Center
April 2018ACTIVE
Biobehavioral mechanisms underlying symptoms and healing outcomes in older individuals with CVLU
September 2017ACTIVE
Evaluating the Tablet-based Turkish-PAINReportIt for Assessing Pain of Lung Cancer Patients Post Thoracotomy in TURKEY
NATL INST OF HLTH NCI · Principal Investigator
September 2017ACTIVE
Double-blind Phase 2 RCT: Effect of Acupuncture on Patient Vulvodynia Outcomes
UNIV OF ILLINOIS · Principal Investigator
September 2016ACTIVE
Dignity Therapy RCT led by Nurses or Chaplains for Elderly Cancer Outpatients
NATL INST OF HLTH NCI · Principal Investigator
July 2016 – January 2018
Protein kinase mechanisms for chronic pain in sickle cell disease
UNIV OF ILLINOIS · Principal Investigator
July 2015ACTIVE
Florida Academic Cancer Center Alliance Seed Grants
February 2015 – May 2019
UNIV OF ILLINOIS · Principal Investigator
February 2015 – August 2017
NORTHWESTERN UNIV · Principal Investigator
February 2015 – April 2017
Computerized PAIN relievelt protocol for cancer pain control in Hospice
UNIV OF ILLINOIS · Principal Investigator
February 2015 – January 2017
UNIV OF ILLINOIS · Principal Investigator
September 2014 – August 2019
Florida Minority Cancer Research and Training Center: Feasibility Studies
NATL INST OF HLTH NCI · Project Manager


Doctor of Philosophy – Nursing, Cancer Pain Management
University of California
Master of Science – Nursing
University of California
Bachelor of Science in Nursing, Cum Laude
Mesa College
Associate Degree in Nursing
University of Hawaii

Contact Details

(352) 273-6401